Phoenix/WinNonlin template for the EMA’s ABEL [Software]
Dear Phoenix-users,
I updated the templates for the EMA’s ABEL (detailed description and download at Certara’s Phoenix WNL basics Forum).
Edit: We (mittyri, Detlew, and myself) realized that the EMA’s SAS-code given in the Q&A document for Method B, i.e.,
If you are using previous versions of the templates: Navigate in the sub-workflow
I updated the templates for the EMA’s ABEL (detailed description and download at Certara’s Phoenix WNL basics Forum).
- New supported designs: RTTR|TRRT, RTR|TRT, and RTT|TRR.
- Checks whether at least 12 subjects are in the sequence RTR (RTR|TRT design) or TRR (RTT|TRR design) as required in the Q&A document Rev.12.
- Removed the meaningless CVwT estimated in a partial replicate design by ‘Method C’ from the output.
Edit: We (mittyri, Detlew, and myself) realized that the EMA’s SAS-code given in the Q&A document for Method B, i.e.,
proc glm data=replicate;
class formulation subject period sequence;
model logDATA= sequence period formulation;
random subject(sequence);
estimate "test-ref" formulation -1 1 / CL alpha=0.10;
run;
model
statement how the degrees of freedom should be estimated. Hence, SAS falls back to its default ddfm=CONTAIN
. It seems that in Phoenix this is equivalent to Residual
.If you are using previous versions of the templates: Navigate in the sub-workflow
Analysis|Standard Average BE|Other Methods
to object BE Method B log
and in the tab General Options
change Degrees of Freedom from ⦿ Satterthwaite
to ⦿ Residual
.—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes