multiple-dosed study with bear [🇷 for BE/BA]

posted by yjlee168 Homepage – Kaohsiung, Taiwan, 2016-10-11 12:15 (2725 d 04:20 ago) – Posting: # 16718
Views: 12,251

Dear Vstus,

I just run the demo of multiple-dose with bear. It is ok. Please make sure that your Tlast is set correctly (the dosing interval looks fine). For example, the following case has Tlast = 120 and dosing interval = 24.

 Time      conc.
  0.0       0.00
 72.0     283.80
 96.0     319.33
120.0     298.06
120.5     634.75
121.0     792.06
121.5     825.69
122.0     900.31
122.5    1083.75
123.0    1273.44
124.0    1475.38
126.0    1981.88
128.0    1669.88
130.0    1324.44
132.0    1052.69
144.0     245.91


BTW, in your setting why dose (mg)?      dose? The dose should be numeric in the unit of mg.

All the best,
-- Yung-jin Lee
bear v2.9.1:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here

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