What is the role of caffeine in bioequivalence studies? [Dissolution / BCS / IVIVC]

posted by Mauricio Sampaio  – Brazil, 2016-05-18 19:43 (2892 d 12:17 ago) – Posting: # 16327
Views: 6,615

Hello for all!

I would like to confirm an information with experts in BCS....
Caffeine is a reference standard to determine the biopharmaceutical classification of other drugs according with solubility and permeability?

If yes, this is a possible reason thcat support the FDA to classify caffeine as an effective substance which there are no bioequivalence problems?

I really appreciate any colaboration ( with references, if is possible) , because I would like to understand why is not need to measure caffeine in bioequivalence studies.

Best regards.

Complete thread:

UA Flag
Activity
 Admin contact
22,987 posts in 4,824 threads, 1,664 registered users;
89 visitors (0 registered, 89 guests [including 4 identified bots]).
Forum time: 08:01 CEST (Europe/Vienna)

The only way to comprehend what mathematicians mean by Infinity
is to contemplate the extent of human stupidity.    Voltaire

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5