Bioequivalence and Bioavailability Forum • RTFM

RTFM [🇷 for BE/BA]

posted by Helmut – Vienna, Austria, 2016-04-07 18:09 (2933 d 21:06 ago) – Posting: # 16172
Views: 8,300

H BE-proff,

❝ Could you share a sample of script for calculation?

As Detlew wrote above

❝ ❝ More arguments of the sample size estimation functions in PowerTOST you may find in the man pages.

Type help(package=PowerTOST) in the R-console or use the online-version. Most interesting functions are sampleN.TOST() for ABE, sampleN.scABEL() for the EMA’s ABEL, and sampleN.RSABE() for the FDA’s RSABE.
At the end of all man pages you will find examples.

❝ How to write design type in it? :confused:

RTFM (argument design) of the sampleN-functions:

sampleN.TOST
Character string describing the study design.
See known.designs() for designs covered in this package.
sampleN.scABEL and sampleN.RSABE
Design of the study to be planned.
2x3x3 is the partial replicate design (TRR|RTR|RRT).
2x2x3 is the 3-period replicate design (TRT|RTR).
2x2x4 is the full replicate design with 2 sequences and 4 periods.
Defaults to design="2x3x3"

Get others from known.designs(). The column design shows the argument to specify in the functions (e.g., design="2x2x2" or design="parallel").

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Complete thread:

PowerTOST for steady state BE-proff 2016-04-06 21:39
- PowerTOST for steady state d_labes 2016-04-07 10:54
  - PowerTOST for steady state BE-proff 2016-04-07 15:42
    - RTFMHelmut 2016-04-07 16:09
      - RTFM BE-proff 2016-04-09 20:15
        
        RTFM‼ Helmut 2016-04-10 00:50
        
        RTFM‼ BE-proff 2016-04-10 13:42
        
        RTFM‼ Helmut 2016-04-10 13:48
        
        RTFM‼ BE-proff 2016-04-12 13:36