Using IVIVC data of different salts and strengths of diclofenac [Dissolution / BCS / IVIVC]
Dear All,
I would be grateful if I could get answers to following queries,
I need to develop a research formulation and could not find a satisfactory answer in the literature that's why i need guidance in this regard.
thanks and regards
I would be grateful if I could get answers to following queries,
- Can 100 mg diclofenac sodium IVIVC data be used to predict the in-vivo performance of 100 mg diclofenac potassium formulation?
- If we have IVIVC data for 50 mg diclofenac potassium, can it be used for 100 mg formulation given that the excipients are also different?
I need to develop a research formulation and could not find a satisfactory answer in the literature that's why i need guidance in this regard.
thanks and regards