Sequential trial with B method of Potvin [Two-Stage / GS Designs]

posted by john john – Spain, 2015-10-07 13:26 (3096 d 04:12 ago) – Posting: # 15524
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Hi

Sorry for the delay. I give you our numbers: n1 was 36 subjects balanced 18RT and 18TR

Cmax   CVintrasub (0.387)  Ratio(%Ref) (81.439)
               BEQ (70.162-94.529)
              Power at 20% (0.715)

AUC0-t CVintrasub (0.324)  Ratio(%Ref) (110.662)
              BEQ (97.552-125.534)
             Power at 20% (0.846)

AUC0-30       BEQ (84.314-105.609)


Thanks for your help

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