## Another suggestion for a R-solution [General Sta­tis­tics]

Dear Detlew,

Master !!!

» ... (only base R,

Even better! I remembered that there was a presentation or file about R for regulated use (or called something similar, couldn't remember. I'll search it later) indicating FDA was using R for analysis and recommended (?) only base R.

» Encapsulating this in a function, adding the BE decision (critbound <0 and sRatioCI[2]<=2.5 in case of NTID's) and output (printing) of details for use in a statistical report is left as your homework .

I'll try

» BTW: EMAI is not NTID with low variability but HVD (CVwR = se2CV(swR)).

I know. But I don't have any project with NTID (one of the reasons I waited until now to read the warfarin guidance in detail) so for coding and validating purpose EMA data should be ok.

All the best,
Shuanghe