Help calculate IVIVC [Dissolution / BCS / IVIVC]

posted by Pharmacist – 2008-01-15 02:00 (5943 d 23:31 ago) – Posting: # 1517
Views: 5,918

Dear Experts,
I have re-read themes of a forum and have come to conclusion what to calculate in my case IVIVC - it is impossible. It is necessary to have necessarily referential pharmacokinetic data (Oral, IV or Infusion). I have decided to simulate these data having substituted approximate average value. On a bookmark in vitro for Internal Validation I put TabA and TabB, as model I took - model Hill's (though it incorrectly actually, I so think).
Whether correctly I do?

And one more question:
I have discovered paper: http://www.locumusa.com/pdf/members/ivivc-01.pdf
In it to be said, that exists Biopharmaceutics Drug Classification for Extended Release Drug Products. Where it is possible to read more in detail about this classification, for Extended Release Drug Products and on how many officially it can use?

Thank's for help!

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