post hoc power [Power / Sample Size]

posted by VSL – India, 2015-07-01 21:37 (4002 d 08:30 ago) – Posting: # 15008
Views: 12,094

Dear,
It has been seen that In protocol, larger sample size is selected to just pass the study without any scientific justification or selecting high T/R in sample size calculation. Therefore, in many cases, post hoc power is more than 100% or nearly 100%. It is like forced bio-equivalence.
Does regulator seek justification for this?
Thanks and Regards...
VSL


Edit: Category changed; see also this post #1[Helmut]

Complete thread:

UA Flag
Activity
 Admin contact
23,654 posts in 4,992 threads, 1,571 registered users;
150 visitors (0 registered, 150 guests [including 22 identified bots]).
Forum time: 06:07 CEST (Europe/Vienna)

Always listen to experts.
They’ll tell you what can’t be done and why.
Then do it.    Robert A. Heinlein

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5