ANOVA F-test results and regulators [🇷 for BE/BA]

posted by d_labes  – Berlin, Germany, 2015-06-12 17:44 (4021 d 10:56 ago) – Posting: # 14953
Views: 17,141

Huummmm,

❝ Why not just always fit the model with no intercept and type I. The first term is almost guaranteed to have a significant P-value. You can then discuss it as much as you feel like at the nuisance level. Specify Sequence first, and voila here's a nice discussion brewing already :-D You can have a standard answer ready for all procedures.


Didn't get your point. Can you elaborate in slow motion and simple words?

As I see it you can't discuss with regulators that their request is nuisance aka crap aka nonsense. Not if you have to discuss a submission.
Only if you meet one at conferences and have forgotten to take your pills ... :-D

Regards,

Detlew

Complete thread:

UA Flag
Activity
 Admin contact
23,654 posts in 4,992 threads, 1,571 registered users;
136 visitors (0 registered, 136 guests [including 18 identified bots]).
Forum time: 04:40 CEST (Europe/Vienna)

Always listen to experts.
They’ll tell you what can’t be done and why.
Then do it.    Robert A. Heinlein

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5