Reproducing Bear results in Phoenix [🇷 for BE/BA]

posted by mittyri – Russia, 2015-04-14 10:35 (3271 d 09:34 ago) – Posting: # 14681
Views: 29,980

Dear Yung-jin, Helmut and all,

Could you please guide me, I cannot reproduce the results from Bear demo sheet (SingleRep - full replicate design) in Phoenix.
I used the WNL reference template published on this forum.
For Bear the results are (lnCmax only for sake of brevity):
**************** Classical (Shortest) 90% C.I. for lnCmax ****************
        Point Estimate   CI90 lower   CI90 upper
Ratio          106.581       98.364      115.485


For Phoenix:
Source    Ratio_%Ref_  CI_90_Lower  CI_90_Upper
Method C  106.5814736   97.91422516 116.0159363
Method A  106.5814736  101.8775288  111.5026114
Method B  106.5814736  101.8775288  111.5026114


Exploring the dataset I've found that the sequences aren't common RTRT/TRTR, but RTTR/TRRT. Is it important for calculations?


Edit: Category changed. [Helmut]

Kind regards,
Mittyri
Thread locked

Complete thread:

UA Flag
Activity
 Admin contact
22,957 posts in 4,819 threads, 1,636 registered users;
77 visitors (0 registered, 77 guests [including 4 identified bots]).
Forum time: 19:10 CET (Europe/Vienna)

Nothing shows a lack of mathematical education more
than an overly precise calculation.    Carl Friedrich Gauß

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5