Magic ElMaestrolophystic RoadShow [PK / PD]
Hi again!
Sorry, but before we end up in the flame board
This AUC > Cmax is a rule of numb. Or maybe rule of dumb, but has nothing to do with science. Best I can imagine: Marketing. Or something like that.
AUC < Cmax will always apply, as long as I choose the timescale long enough (hours, days, weeks,...) for AUC compared to the terminal half-life of the compound. So this all is utter nonsense, as Maestro pointed out. You can not compare apples and bananas and come up with: apples are sweeter than bananas. Beyond kindergarten...
Sorry, but before we end up in the flame board
This AUC > Cmax is a rule of numb. Or maybe rule of dumb, but has nothing to do with science. Best I can imagine: Marketing. Or something like that.
AUC < Cmax will always apply, as long as I choose the timescale long enough (hours, days, weeks,...) for AUC compared to the terminal half-life of the compound. So this all is utter nonsense, as Maestro pointed out. You can not compare apples and bananas and come up with: apples are sweeter than bananas. Beyond kindergarten...
—
Kindest regards, nobody
Kindest regards, nobody
Complete thread:
- Cmax value higher than AUC msmnainar 2015-02-16 13:41
- Cmax value higher than AUC ElMaestro 2015-02-16 13:46
- Cmax value higher than AUC msmnainar 2015-02-16 13:51
- Cmax value higher than AUC ElMaestro 2015-02-16 14:01
- Cmax value higher than AUC nobody 2015-02-16 14:23
- Cmax value higher than AUC Dr_Dan 2015-02-17 08:11
- Cmax value higher than AUC nobody 2015-02-17 09:38
- Cmax value higher than AUC janmacek 2015-02-17 10:41
- Cmax value higher than AUC nobody 2015-02-17 11:19
- Cmax value higher than AUC msmnainar 2015-02-17 11:36
- Magic ElMaestrolophystic RoadShow ElMaestro 2015-02-17 14:56
- Magic ElMaestrolophystic RoadShow janmacek 2015-02-17 16:02
- Magic ElMaestrolophystic RoadShownobody 2015-02-17 16:32
- Bizarre discussion… Helmut 2015-02-17 17:06
- Bizarre discussion… janmacek 2015-02-17 17:42
- Magic ElMaestrolophystic RoadShow janmacek 2015-02-17 16:02
- Cmax value higher than AUC nobody 2015-02-17 11:19
- Cmax value higher than AUC janmacek 2015-02-17 10:41
- Cmax value higher than AUC Dr_Dan 2015-02-17 18:53
- Cmax value higher than AUC nobody 2015-02-17 20:16
- Cmax value higher than AUC nobody 2015-02-17 09:38
- Cmax value higher than AUC ElMaestro 2015-02-16 14:01
- Cmax value higher than AUC msmnainar 2015-02-16 13:51
- Cmax value higher than AUC ElMaestro 2015-02-16 13:46