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RegisterMagic ElMaestrolophystic RoadShow [PK / PD]
Dear all,
highly distinguished respectable scientists of great reputation,
can we please, please reconnect with the real world?
So AUC<Cmax?
Ladies and gentlemen, I give you:
The Magic ElMaestrolophystic RoadShow.
Coming to a town near you! Starring a handsome Dataset, a magic wand, and an SI unit.
We have AUC<Cmax where
AUC = 38.3 ng*hrs/mL
Let's see... How about converting time to SI units? One hour is 3600 seconds, so
AUC = 38.3 hrs * (3600 s/hrs)ng/mL
*drum roll*
*drum roll*
*drum roll*
*drum roll*
*drum roll*
*drum roll*
*drum roll*
=138*103 ng*s/mL
And we hence conclude that AUC>Cmax.
The Magic ElMaestrolophystic RoadShow has hereby shown that when AUC<Cmax then we can conclude that AUC>Cmax. Hocus Pocus. It is nothing less than black magic....
....and a teeny-tiny dose of complete utter nonsense.
highly distinguished respectable scientists of great reputation,
can we please, please reconnect with the real world?
❝ Cmax = 100 ng/ml
❝ AUC = 38.3 ng·h/ml
So AUC<Cmax?
Ladies and gentlemen, I give you:
The Magic ElMaestrolophystic RoadShow.
Coming to a town near you! Starring a handsome Dataset, a magic wand, and an SI unit.
We have AUC<Cmax where
AUC = 38.3 ng*hrs/mL
Let's see... How about converting time to SI units? One hour is 3600 seconds, so
AUC = 38.3 hrs * (3600 s/hrs)ng/mL
*drum roll*
*drum roll*
*drum roll*
*drum roll*
*drum roll*
*drum roll*
*drum roll*
=138*103 ng*s/mL
And we hence conclude that AUC>Cmax.
The Magic ElMaestrolophystic RoadShow has hereby shown that when AUC<Cmax then we can conclude that AUC>Cmax. Hocus Pocus. It is nothing less than black magic....
....and a teeny-tiny dose of complete utter nonsense.
—
Pass or fail!
ElMaestro
Pass or fail!
ElMaestro
Complete thread:
- Cmax value higher than AUC msmnainar 2015-02-16 13:41
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Cmax value higher than AUC ElMaestro 2015-02-16 13:46
- Cmax value higher than AUC msmnainar 2015-02-16 13:51
- Cmax value higher than AUC ElMaestro 2015-02-16 14:01
- Cmax value higher than AUC nobody 2015-02-16 14:23
- Cmax value higher than AUC Dr_Dan 2015-02-17 08:11
- Cmax value higher than AUC nobody 2015-02-17 09:38
- Cmax value higher than AUC janmacek 2015-02-17 10:41
- Cmax value higher than AUC nobody 2015-02-17 11:19
- Cmax value higher than AUC msmnainar 2015-02-17 11:36
- Magic ElMaestrolophystic RoadShowElMaestro 2015-02-17 14:56
- Magic ElMaestrolophystic RoadShow janmacek 2015-02-17 16:02
- Magic ElMaestrolophystic RoadShow nobody 2015-02-17 16:32
- Bizarre discussion… Helmut 2015-02-17 17:06
- Bizarre discussion… janmacek 2015-02-17 17:42
- Magic ElMaestrolophystic RoadShow janmacek 2015-02-17 16:02
- Cmax value higher than AUC nobody 2015-02-17 11:19
- Cmax value higher than AUC janmacek 2015-02-17 10:41
- Cmax value higher than AUC Dr_Dan 2015-02-17 18:53
- Cmax value higher than AUC nobody 2015-02-17 20:16
- Cmax value higher than AUC nobody 2015-02-17 09:38
- Cmax value higher than AUC ElMaestro 2015-02-16 14:01
- Cmax value higher than AUC msmnainar 2015-02-16 13:51
- Cmax value higher than AUC ElMaestro 2015-02-16 13:46
Ing. Helmut Schütz