Backups; volume of blood during the sampling [Study Per­for­mance]

posted by mittyri – Russia, 2015-02-03 15:28 (3340 d 23:57 ago) – Posting: # 14366
Views: 5,739

Dear All,

I would like to discuss some points during the study conducting which we are faced in one site.
1. Backups.
In this site backups are invited at the beginning of 1st and 2nd periods.
So in case when volunteer was excluded due to some reasons before the beginning of 2nd perod (during the 1st period or during the wash-out), the invited backup starts the 2nd period with other volunteers.
For example: 22 volunteers, one of them (R03, sequence RT) broke his leg during the washout. The backup is invited to the 2nd period, but this backup should be dosed with RIMP, because for him it's a "1st period"! After washout he'll be invited at the "2nd period" and dosed with TIMP.
By the way all biosamples will be analyzed.
For me it looks strange. What do you think about this procedure?

2. During the sampling a nurse inject little volume of heparine solution to catheter after each blood draw. To avoid the contact of heparin solution and vacutainer the nurse takes away little volume of blood before each next blood drawing.
What do you think? Is it really necessary to remove 'heparinized' blood from the catheter?

Kind regards,
Mittyri

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