SAS/R code of MSD method for comparing dissolution [Dissolution / BCS / IVIVC]
Hi arjunroy,
for pooled variance, instead of using (st + sr) / 2, it's better to use:
sp = ((nt-1)*st + (nr-1)*sr)/(nt+nr-2)
This works regardless if nt = nr.
I use SAS 9.2 and the COV module defined as above worked. It seems version 9.1.3 didn't support operation for matrix with different dimensions therefore the line
gave error you had. Weird.
You can try the following code:
The
You can report it back here if it works.
❝ Thank you
for pooled variance, instead of using (st + sr) / 2, it's better to use:
sp = ((nt-1)*st + (nr-1)*sr)/(nt+nr-2)
This works regardless if nt = nr.
❝ Here is SAS IMLv9.1.3 log error for your perusal.
❝ ......
I use SAS 9.2 and the COV module defined as above worked. It seems version 9.1.3 didn't support operation for matrix with different dimensions therefore the line
d = m - m[:,];
gave error you had. Weird.
You can try the following code:
START COV(m);
n = NROW(m);
d = m - REPEAT(m[:,],n,1);
RETURN((d`*d)/(n-1));
FINISH;
The
REPEAT
function will create a matrix with n rows with each row equal to the mean profile. Then the matrix will be of same dimensions for the subtraction to work. You can report it back here if it works.
—
All the best,
Shuanghe
All the best,
Shuanghe
Complete thread:
- SAS/R code of MSD method for comparing dissolution Shuanghe 2014-02-10 17:05
- Wow, what a gem! Helmut 2014-02-10 17:15
- SAS/R code of MSD method for comparing dissolution arjunroy 2014-12-19 10:56
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- SAS/R code of MSD method for comparing dissolution arjunroy 2014-12-22 05:42
- SAS/R code of MSD method for comparing dissolutionShuanghe 2014-12-24 11:09
- SAS/R code of MSD method for comparing dissolution arjunroy 2014-12-24 11:44
- SAS/R code of MSD method for comparing dissolution Shuanghe 2015-01-08 11:16
- SAS/R code of MSD method for comparing dissolution arjunroy 2014-12-24 11:44
- SAS/R code of MSD method for comparing dissolutionShuanghe 2014-12-24 11:09
- SAS/R code of MSD method for comparing dissolution arjunroy 2014-12-22 05:42
- SAS/R code of MSD method for comparing dissolution Shuanghe 2014-12-19 17:13
- SAS/R code of MSD method for comparing dissolution wligtenberg 2016-12-12 14:09
- SAS/R code of MSD method for comparing dissolution Shuanghe 2016-12-19 19:03
- SAS/R code of MSD method for comparing dissolution wligtenberg 2016-12-20 08:14
- SAS/R code of MSD method for comparing dissolution Shuanghe 2016-12-22 09:23
- SAS/R code of MSD method for comparing dissolution wligtenberg 2016-12-22 11:20
- SAS/R code of MSD method for comparing dissolution Shuanghe 2016-12-22 09:23
- SAS/R code of MSD method for comparing dissolution Olga 2018-04-21 07:01
- SAS/R code of MSD method for comparing dissolution wligtenberg 2016-12-20 08:14
- SAS/R code of MSD method for comparing dissolution Shuanghe 2016-12-19 19:03