Bioequivalence and Bioavailability Forum • Difference between Cminss and Ctauss?

Difference between Cminss and Ctauss? [NCA / SHAM]

posted by tekwani.sunil – India, 2014-12-04 06:53 (3429 d 19:44 ago) – Posting: # 13975
Views: 5,184

Thanks Helmut,

Thanks for the help. If 90% confidence interval falls between 80-125% for only Cminss but not for Ctauss, what justification can be given?

Can it be justified that the submission is done before the implementation of new MR guideline (which is effective from 1 June 2015), so 90% CI of Cminss should be considered?

Complete thread:

Difference between Cminss and Ctauss? tekwani.sunil 2014-12-03 07:10
- Difference between Cminss and Ctauss? Helmut 2014-12-03 13:11
  - Difference between Cminss and Ctauss?tekwani.sunil 2014-12-04 05:53
    - Difference between Cminss and Ctauss? Helmut 2014-12-04 14:21