Bioequivalence and Bioavailability Forum

Main page Policy/Terms of Use Abbreviations Latest Posts

 Log-in |  Register |  Search

Back to the forum  Query: 2017-11-24 13:53 CET (UTC+1h)
 

Difficulties with NCA BEAR [R for BE/BA]

posted by PK_Lover - Portugal, 2014-11-21 00:28  - Posting: # 13895
Views: 8,873

Hello all,

I am trying BEAR for the first time for a simple NCA and ANOVA analysis for a 2x2x2 BE study data.

I have arranged all the data in a .csv file with subj,seq,perd,time,conc and I have maintained T0=0 and all the other LLOQ (either at the start of the schedule or at the end) as NA.

I ran BEAR, import the file, the values appear correctly in the table. It starts the analysis, it shows some pk values but then states:

Error in lm.fit(x, y, offset = offset, singular.ok = singular.ok, ...) :
  NA/NaN/Inf in 'y'


and crashes. I have checked all the data, seems ok.

Could you please help me and tell me whats wrong?

Thank you!

Complete thread:

Back to the forum Activity
 Mix view
Bioequivalence and Bioavailability Forum | Admin contact
17,495 Posts in 3,746 Threads, 1,085 registered users;
30 users online (1 registered, 29 guests).

The belief that there is only one truth and
that oneself is in possession of it,
seems to me the deepest root of all
that is evil in the world.    Max Born

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
XHTML/CSS RSS Feed