Difficulties with NCA BEAR [R for BE/BA]

posted by PK_Lover – Portugal, 2014-11-21 00:28  – Posting: # 13895
Views: 15,376

Hello all,

I am trying BEAR for the first time for a simple NCA and ANOVA analysis for a 2x2x2 BE study data.

I have arranged all the data in a .csv file with subj,seq,perd,time,conc and I have maintained T0=0 and all the other LLOQ (either at the start of the schedule or at the end) as NA.

I ran BEAR, import the file, the values appear correctly in the table. It starts the analysis, it shows some pk values but then states:

Error in lm.fit(x, y, offset = offset, singular.ok = singular.ok, ...) :
  NA/NaN/Inf in 'y'


and crashes. I have checked all the data, seems ok.

Could you please help me and tell me whats wrong?

Thank you!

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