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Registerdifficulty of understanding HVDPs [RSABE / ABEL]
Hi Everybody , I have big problem to understand what's HVDP's
soI read : HVDPs are products in which the drug is not highly variable, but the product is of poor pharmaceutical quality and high within-formulation variability, so What’s the difference between : Within formulation variability and Subject by formulation interaction? Is subject by formulation interaction contribute to high CVW ( >30%) in HVDPs?
I confounds between the two , for me subject by formulation interaction is inter-individual variability, when the excipients in a formulation influence physiological variables, or the physicalchemical properties of a formulation and/or its drug, in the gastro intestinal tract
thank you :)
soI read : HVDPs are products in which the drug is not highly variable, but the product is of poor pharmaceutical quality and high within-formulation variability, so What’s the difference between : Within formulation variability and Subject by formulation interaction? Is subject by formulation interaction contribute to high CVW ( >30%) in HVDPs?
I confounds between the two , for me subject by formulation interaction is inter-individual variability, when the excipients in a formulation influence physiological variables, or the physicalchemical properties of a formulation and/or its drug, in the gastro intestinal tract
thank you :)
Complete thread:
- difficulty of understanding HVDPskhaoula 2014-09-08 15:01 [RSABE / ABEL]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- difficult to mee too ElMaestro 2014-09-08 15:47
- HVDs ≠ HVDPs Helmut 2014-09-13 18:49
- HVDs ≠ HVDPs khaoula 2014-09-13 19:44
Ing. Helmut Schütz