Imbalanced cross-overs [Study Performance]
Patient Sequence CmaxT CmaxR LnCmaxT LnCmaxR
1 RT 745 765 6.613 6.640
2 RT 302 216 5.710 5.370
3 TR 775 633 6.653 6.450
4 TR 628 468 6.443 6.148
5 TR 566 569 6.504 6.344
6 TR 546 525 6.303 6.263
7 RT 176.86 307 5.175 5.720
8 RT 531 363 6.275 5.894
9 RT 518 243 6.250 5.493
10 RT 572 419 6.349 6.038
11 TR 704 371 6.557 5.916
12 TR 694 705 6.542 6.558
13 TR 1400 1180 7.244 7.073
14 RT 745 765 6.613 6.640
15
16 TR 339 232 5.826 5.447
latin square of Cmax
SOURCE D.F SS MS F p
Period 1 0.0264787 0.0264787 0.56186 0.4669 NS
Subject(Seq) 13 4.8517 0.373208 7.91934 0.0003379 ***
Formulation 1 0.211625 0.211625 4.4906 0.05391 NS
Sequence 1 0.686301 0.686301 14.5631 0.002141 ***
Error 13 0.61264 0.0471261
Total 29 6.38875
Root Mean Square Error = 0.217086 ; CV = 0.0347883
phi = 1.49843
Power of the test = 0.500777
1 - ( Power of the test ) = 0.499223
around the ratio:[test form]/[ref form])=[1.028, 1.3612]
I havnt randomisation of subject 15, and then they put the result in kinetica they excluded him, they havnt protocol for outlier etc
thank you
Complete thread:
- randomization khaoula 2014-06-06 14:04
- Imbalanced cross-overs Helmut 2014-06-06 14:47
- Imbalanced cross-overs khaoula 2014-06-06 16:03
- CV 0.03%? Helmut 2014-06-07 13:52
- Imbalanced cross-overs jag009 2014-06-09 15:36
- Imbalanced cross-overskhaoula 2014-06-09 22:07
- Bag full of bugs Helmut 2014-06-10 00:37
- Randomisation? ElMaestro 2014-06-10 01:00
- Randomisation? Helmut 2014-06-10 14:53
- Randomisation? khaoula 2014-06-11 00:17
- Problems resolved? Helmut 2014-06-11 02:01
- Problems resolved? khaoula 2014-07-24 13:36
- corrected data in PHX/WNL Helmut 2014-07-27 01:37
- Problems resolved? khaoula 2014-07-24 13:36
- Problems resolved? Helmut 2014-06-11 02:01
- Randomisation? khaoula 2014-06-11 00:17
- Randomisation? Helmut 2014-06-10 14:53
- Randomisation? ElMaestro 2014-06-10 01:00
- Which version of Kinetica? Helmut 2014-06-11 19:51
- Which version of Kinetica? khaoula 2014-06-12 00:41
- Which version of Kinetica? khaoula 2014-07-25 00:49
- adjusted means (aka LSMs) Helmut 2014-07-27 02:23
- adjusted means (aka LSMs) khaoula 2014-08-25 21:41
- adjusted means (aka LSMs) Helmut 2014-07-27 02:23
- Bag full of bugs Helmut 2014-06-10 00:37
- Imbalanced cross-overskhaoula 2014-06-09 22:07
- Imbalanced cross-overs khaoula 2014-06-06 16:03
- Imbalanced cross-overs Helmut 2014-06-06 14:47