Bioequivalence and Bioavailability Forum

Errors happen [NCA / SHAM]

posted by d_labes  – Berlin, Germany, 2014-03-20 09:26 (4464 d 14:48 ago) – Posting: # 12674
Views: 24,798

Dear mittyri,

❝ I cannot undestand these formulas:

❝ ❝ 2.1. Calculation of C_last

❝ ❝ - ref (last time = 24.00)

❝ ❝ : 0.82 X (-0.20027)+4.60838 = -0.19804

❝ 0.82 X (-0.20027)+4.60838 = 4.4442

❝ <...>

❝ ❝ - test (last time = 16.92)

❝ ❝ : 3.22 X (-0.19992)+4.55224 = 1.16956

❝ 3.22 X (-0.19992)+4.55224 = 3.9085

Me too !
You are absolutely correct in questioning these formulas. What here would be correct is:
24*(-0.20027)+4.60838 = -0.1981
and
16.92*(-0.19992)+4.55224=1.169594

Complete thread:

• Calculation of AUCt yckim 2007-11-27 02:46 [NCA / SHAM] 
  • Calculation of AUCt, AUCall, AUCinf... Helmut 2007-11-27 22:02
    • Calculation of AUCt, AUCall, AUCinf... yckim 2007-11-28 02:44
      • Calculation of AUCt, AUCall, AUCinf... Helmut 2007-11-28 03:49
        • Calculation of AUCt, AUCall, AUCinf... jmlee 2008-10-10 08:29
          • Calculation of AUCt, AUCall, AUCinf... Helmut 2008-10-10 17:48
          • Calculation of AUCt, AUCall, AUCinf... mittyri 2014-03-19 19:15
            • Errors happend_labes 2014-03-20 08:26
              • Errors happen fno 2014-03-20 11:03
    • Calculation of AUCt, AUCall, AUCinf... Ohlbe 2007-11-28 10:37
      • Calculation of AUCt, AUCall, AUCinf... Helmut 2007-11-28 12:28
        • References Helmut 2007-11-28 17:58