TRT|RTR or FA0(1) [RSABE / ABEL]
Hi John,
Overspecified model – see this lengthy thread. I think you have two options:
Me not either. But I’m pretty sure the partial replicate is crap.
❝ When I switched to FA0(1) then it worked. […] same as yours.
❝
❝ Question is why FA0(2) didn't work?
Overspecified model – see this lengthy thread. I think you have two options:
- Avoid the partial replicate in the future. Run the fully replicated three-period TRT|RTR instead. That’s what the Lászlós recommend. Go ahead with
FA0(2)
; no convergence issues on the way. Compliant with the guidance? Duno. You can stick to the code, but the design is not mentioned…
- If you already have the data on your desk, switch to
FA0(1)
. Unlike ElMaestro I don’t think that you will be successful tweaking the side conditions in SAS (convergence criteria, no. of iterations, whatsoever). At least in PHX/WNL it never worked. Compliant with the guidance? If you believe devoutly that you have to follow the code literally – no.
But: That’s your only chance to get a result in SAS. For your current study you could additionally show the results obtained in PHX/WNL withFA0(2)
– which worked like a charm this time (by luck).
❝ I am not a saint in statistics yet so I don't know.
Me not either. But I’m pretty sure the partial replicate is crap.
—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- tada: Another issue with FDA's RSABE (please confirm?) jag009 2013-12-19 17:41 [RSABE / ABEL]
- Phoenix/WinNonlin: not confirmed Helmut 2013-12-20 04:13
- Phoenix/WinNonlin: not confirmed jag009 2013-12-20 17:12
- TRT|RTR or FA0(1)Helmut 2013-12-20 17:37
- TRT|RTR or FA0(1) jag009 2013-12-20 21:24
- Partial replicate crap? Really? d_labes 2013-12-23 09:18
- Partial replicate crap? Really? Helmut 2013-12-23 14:06
- TRT|RTR or FA0(1)Helmut 2013-12-20 17:37
- Phoenix/WinNonlin: not confirmed jag009 2013-12-20 17:12
- Tweak & Fiddle ElMaestro 2013-12-20 14:32
- Tweak & Fiddle jag009 2013-12-20 17:16
- Not confirmed - SAS d_labes 2013-12-23 10:14
- Phoenix/WinNonlin: not confirmed Helmut 2013-12-20 04:13