IVIVC calculations [Dissolution / BCS / IVIVC]

posted by mahendra – US, 2013-10-24 18:10 (3808 d 07:06 ago) – Posting: # 11753
Views: 37,698

Hi
I am working in analytical method development for Pharmaceutical company.

I want to just learn how to do IVIVC comparison.

For a Batch of drug product:

for Invitro: data: % drug dissolved in 15 min, 30 min, 45 min intervals.
For invivo: What data do i need ? Like AUC, Cmax etc.

I am unbale to see examples on this. Colud any one help me to learn this? Its my interest.

I have Minitab 16: is it capble to IVIVC?

I see recently in a post that mentioned IVIVC is possible in R software? I dont know about R software and i have not used it? Is it simple to run IVIVC in R to learn?

I want to see practically how IVIVC data give the information for next development?

Thanks in advance

Complete thread:

UA Flag
Activity
 Admin contact
22,957 posts in 4,819 threads, 1,636 registered users;
80 visitors (0 registered, 80 guests [including 7 identified bots]).
Forum time: 00:17 CET (Europe/Vienna)

Nothing shows a lack of mathematical education more
than an overly precise calculation.    Carl Friedrich Gauß

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5