estimated AUC72 [NCA / SHAM]
Dear All,
The study was for combination of Fluticasone+Salmeterol pMDI with and without charcoal treatment (first two periods were without charcoal and last two periods were with charcoal) and the problem of extrapolation was majorly seen in with charcoal treatment periods for Salmeterol component and the AUC was calculated by Phoenix/WinNonlin using log-linear trapezoidal method.
Regards,
Ratnakar
The study was for combination of Fluticasone+Salmeterol pMDI with and without charcoal treatment (first two periods were without charcoal and last two periods were with charcoal) and the problem of extrapolation was majorly seen in with charcoal treatment periods for Salmeterol component and the AUC was calculated by Phoenix/WinNonlin using log-linear trapezoidal method.
Regards,
Ratnakar
Complete thread:
- Actual time for PK analysis ratnakar1811 2013-10-07 08:07
- estimated AUC72 Helmut 2013-10-07 13:36
- estimated AUC72 ratnakar1811 2013-10-08 08:20
- estimated AUC72 sam 2013-10-08 13:15
- estimated AUC72 Helmut 2013-10-08 13:51
- estimated AUC72 ratnakar1811 2013-10-10 11:30
- estimated AUC72 jag009 2013-10-13 21:17
- estimated AUC72 ratnakar1811 2013-10-15 06:23
- estimated AUC72 Dr_Dan 2013-10-15 12:24
- estimated AUC72 jag009 2013-10-15 21:53
- estimated AUC72ratnakar1811 2013-10-17 09:34
- estimated AUC72 ratnakar1811 2013-10-15 06:23
- estimated AUC72 jag009 2013-10-13 21:17
- estimated AUC72 ratnakar1811 2013-10-10 11:30
- estimated AUC72 ratnakar1811 2013-10-08 08:20
- estimated AUC72 Helmut 2013-10-07 13:36