estimated AUC72 [NCA / SHAM]

posted by ratnakar1811 – India, 2013-10-17 11:34 (3815 d 07:27 ago) – Posting: # 11670
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Dear All,
The study was for combination of Fluticasone+Salmeterol pMDI with and without charcoal treatment (first two periods were without charcoal and last two periods were with charcoal) and the problem of extrapolation was majorly seen in with charcoal treatment periods for Salmeterol component and the AUC was calculated by Phoenix/WinNonlin using log-linear trapezoidal method.
Regards,

Ratnakar

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