SAS vs. PHX [RSABE / ABEL]

posted by Helmut Homepage – Vienna, Austria, 2013-04-23 00:10 (3992 d 13:11 ago) – Posting: # 10466
Views: 21,980

Hi John,

❝ My SAS SCABE for this parameter is

Theta    Bound y  (S2wr)    (sWR)   (T/R) Pt Est  95% Upper Crit

0.79669 -0.22198  0.41135  0.64137    89.8994     -0.18423


No need to post Theta (a constant in RSABE). ;-)

My PHX6.3 code gives for RSABE …
boundy     S²wr     Swr       PE       95% upper
-0.221998  0.41138  0.64139  89.8990  -0.18424336


❝ I ran Unscaled Avg BE (Progesterone guidance SAS code)

T/R Ratio     90% CI

101.021    80.7739 - 126.343


… and for ABE
  PE          90% CI
104.782  69.7855 – 157.328


But: PHX’ LME kicked my ass with “Warning 11094: Negative final variance component. Consider omitting this VC structure.” Nice. Old story with partial replicates – overspecified model since T is not repeated. We have seen in the past that SAS and PHX give different results in such a case. BTW, did you get “Convergence criteria met but final hessian is not positive definite.” or somefink similar in Sas?

If I go with the ABE-module I got:
ERROR 11070:  Error in Satterthwaite DF. Try using Residual DF option.
… which I tried, only to get:
ERROR 11070:  Error in Satterthwaite DF. Try using Residual DF option.
That’s funny! Same if I exclude subjects #14 and #31 (no results for T). What the heck?

Running PHX’ PBE/IBE module I first obtained …
Warning 11121: Subject 31 had incomplete design and was discarded.
Warning 11121: Subject 14 had incomplete design and was discarded.
Warning 11121: Subject 8 had incomplete design and was discarded.
Warning 11121: Subject 17 had incomplete design and was discarded.


… and a PE which is exactly like in RSABE 89.899043.

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