Bioequivalence and Bioavailability Forum

Two Stage Desing: ANOVA [Two-Stage / GS Designs]

posted by earlybird – 2009-10-16 13:25 (6086 d 00:35 ago) – Posting: # 4367
Views: 14,580

Dear all,

we are planning a two-stage Design according Method B, Diane Potvin. Does somebody know if the ANOVA statement has to be adapted? I.E. to add stage, stage-treatment interaction as fixed effects and subject nested within (stage x sequence) as random effect.

Earlybird

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The answer: Please find solution on Page 9 of Potvin paper. Thanks to Berlin!

earlybird

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Edit: I restored your original post – otherwise my reply might be confusing. [Helmut]

Complete thread:

• Two Stage Desing: ANOVAearlybird 2009-10-16 11:25 [Two-Stage / GS Designs] 
  • Potvin et al: effects in stage 2 Helmut 2009-10-16 13:32
    • Potvin et al: effects in stage 2 d_stat 2021-07-19 16:26
      • Forget simulation-based TSDs for 2×2×2 in Europe Helmut 2021-07-19 17:22
        • TSD statistical model - with multiple sites d_stat 2021-07-20 13:58
          • TSD statistical model - with multiple sites Helmut 2021-07-20 21:52
            • TSD statistical model - with multiple sites d_stat 2021-10-11 17:48
              • TSD statistical model - with multiple sites Helmut 2021-10-12 11:27