Bioequivalence and Bioavailability Forum • CVintra for Cmax > AUC, therefore use AUC for sample size?

CVintra for Cmax > AUC, therefore use AUC for sample size? [Power / Sample Size]

posted by nobody – 2017-08-07 19:14 (2888 d 07:53 ago) – Posting: # 17673
Views: 11,037

Hi again!

Found this here:

https://www.ncbi.nlm.nih.gov/pubmed/28257283

Maybe I need some holiday, after all, but if I understand this correctly, the authors say, CVintra for Cmax is generally higher than for AUC, therefore use AUC to estimate the sample size of your study.

Did I get this right?

Any thoughts on this approach?

—
Kindest regards, nobody

Complete thread:

CVintra for Cmax > AUC, therefore use AUC for sample size?nobody 2017-08-07 17:14 [Power / Sample Size]
- CVintra for Cmax > AUC, therefore use AUC for sample size? Helmut 2017-08-07 18:40
  - CVintra for Cmax > AUC, therefore use AUC for sample size? nobody 2017-08-07 19:52
    - Crap… Helmut 2017-08-07 20:29
      - Crap… nobody 2017-08-07 21:31
- CVintra for Cmax > AUC, therefore use AUC for sample size? ElMaestro 2017-08-07 23:04
  - CVintra for Cmax > AUC, therefore use AUC for sample size? nobody 2017-08-08 10:06
- CVintra for Cmax > AUC, therefore use AUC for sample size? jag009 2017-08-09 06:21
  - CVintra for Cmax > AUC, therefore use AUC for sample size? nobody 2017-08-09 17:11