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RegisterTherapeutic equivalence? [Design Issues]
Dear d_labes
not all anti-cancer drugs are cytotoxic, for example aromatase inhibitors for treating breast cancer or imatinib, a phenylaminopyrimidine derivative, which is a selective inhibitor of the tyrosine kinase activity of BCR-ABL fusion gene (oncoprotein), the product of the Philadelphia chromosome. You can test these drugs in healthy subjects, no problem. Other drugs like capecitabine or temozolomide can only be tested in patients. So it depends.
Dan
not all anti-cancer drugs are cytotoxic, for example aromatase inhibitors for treating breast cancer or imatinib, a phenylaminopyrimidine derivative, which is a selective inhibitor of the tyrosine kinase activity of BCR-ABL fusion gene (oncoprotein), the product of the Philadelphia chromosome. You can test these drugs in healthy subjects, no problem. Other drugs like capecitabine or temozolomide can only be tested in patients. So it depends.
Dan
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Kind regards and have a nice day
Dr_Dan
Kind regards and have a nice day
Dr_Dan
Complete thread:
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- Therapeutic equivalence? d_labes 2011-02-08 10:37
- Therapeutic equivalence?Dr_Dan 2011-02-08 14:40
- Therapeutic equivalence? d_labes 2011-02-08 14:45
- Therapeutic equivalence? bjkim97 2011-02-23 11:06
- Therapeutic equivalence? Dr_Dan 2011-02-28 14:53
- Therapeutic equivalence? bjkim97 2011-03-03 12:37
- Therapeutic equivalence? Dr_Dan 2011-02-28 14:53
- Therapeutic equivalence? Mauricio Sampaio 2024-06-17 02:21
- Therapeutic equivalence?Dr_Dan 2011-02-08 14:40
- Therapeutic equivalence raghu 2011-02-09 10:07
- Therapeutic equivalence? d_labes 2011-02-08 10:37
Ing. Helmut Schütz