Bioequivalence and Bioavailability Forum • Moses CI

Moses CI [Nonparametrics]

posted by Dr Andrew Leary – Ireland, 2009-01-27 12:41 (6346 d 02:55 ago) – Posting: # 3136
Views: 19,555

Thank you both for your responses.

I had not picked up that point during my hasty reading of the new (draft) guideline, Helmut, but saw your extensive discussions of same when looking at the forum yesterday evening.

At present all our BE protocols stick with the old guideline and require non-parametric assessment of Tmax. I can foresee a time in 2 years when we'll have to repeat part of every analysis to provide parametric results. Are you sure that this aspect of the new guideline will stick? I'm a clinician not a statistician, but it seems to me that perfroming parametric stats on a small amount of categorical data flies in the face of traditional teaching.

Kind regards

Andrew

--
Edit: Full quote removed. Please see this post! [Helmut]

Complete thread:

Hodges-Lehmann Point Estimate Dr Andrew Leary 2009-01-26 18:18
- Moses CI Helmut 2009-01-26 19:43
  - Moses CI Dr Andrew Leary 2009-01-26 19:51
    - Moses CI Helmut 2009-01-26 20:08
  - Moses CI martin 2009-01-27 11:25
    - Moses CIDr Andrew Leary 2009-01-27 11:41
      - Moses CI Helmut 2009-01-27 12:04
    - Moses CI in the "power to know" d_labes 2009-01-27 12:10
      - Moses CI in the "power to know" Dr Andrew Leary 2009-01-27 12:33
    - Moses CI Helmut 2009-01-27 12:39
      - Deckerian CI d_labes 2009-01-27 13:22
        
        Deckerian CI martin 2009-01-27 19:10
        
        Transformers d_labes 2009-01-28 15:32