Log in
RegisterTmax [Nonparametrics]
Hi Chidambarajoshi,
you need to tell us a little more. Only a stat. analysis* can tell if this is stat. significant. To find out if it is clinically significant you might want to apply common sense and judgment (which regulators seem to hate to apply to their assessments).
Usually Tmax is given some regard in evaluations, unless a protocol for some reason specifes something else.
Having said all that, a 6 hrs. difference does not exactly sound promising.
EM.
*: Many companies actually just use Wilcoxon
you need to tell us a little more. Only a stat. analysis* can tell if this is stat. significant. To find out if it is clinically significant you might want to apply common sense and judgment (which regulators seem to hate to apply to their assessments).
Usually Tmax is given some regard in evaluations, unless a protocol for some reason specifes something else.
Having said all that, a 6 hrs. difference does not exactly sound promising.
EM.
*: Many companies actually just use Wilcoxon
Complete thread:
- Tmax chidambarajoshi 2008-08-13 10:02
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- TmaxElMaestro 2008-08-13 10:25
- Tmax chidambarajoshi 2008-08-13 10:49
- Tmax (EU) Helmut 2008-08-13 13:48
- Tmax (EU) chidambarajoshi 2008-08-14 06:30
- Tmax (WinNonlin) Helmut 2008-08-14 20:12
- Tmax (WinNonlin) chidambarajoshi 2008-08-25 09:47
- Tmax (WinNonlin) SDavis 2008-11-18 19:47
- Tmax (WinNonlin) Helmut 2008-11-18 20:15
- Tmax (Phoenix WinNonlin 6.0/6.1) Helmut 2009-06-12 18:55
- Tmax (WinNonlin) Helmut 2008-08-14 20:12
- Tmax (EU) chidambarajoshi 2008-08-14 06:30
- Tmax (EU) Helmut 2008-08-13 13:48
- Tmax chidambarajoshi 2008-08-13 10:49
- TmaxElMaestro 2008-08-13 10:25
Ing. Helmut Schütz