Bioequivalence and Bioavailability Forum

Hi M.Y.,

❝ I want to know whether we can use transformed data on Tmax to check for CI?. AS it was stated previously that if we will take Tmax into statistical considerations we will take untransformed tmax not transformed ones.

CI's on Tmax are not much in use anymore. Don't bother.
I mainly see them popping up nowadays when applicants find themselves in desperate situations with deficiency letters and imminent rejection fears. That's when they try to generate all sorts of supportive funky BE results (which were never stipulated in any protocol or SAP) in the hope that quantity of tests outweighs the quality of a few well-chosen tests.