Bioequivalence and Bioavailability Forum

Thanks Helmut: I will look at that paper. What we are seeking is a measure of the variability of the Tmax paramater in the test formulation and the variability of the Tmax parameter in the reference formulation. The data comes from a cross-over design.

In the absence of a distribution. One can do a frequency plot and a percentile analysis and simply compare to see if one is less variable than the other................


Angus