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Registerdose selection to investigate dose-proportionality [Surveys]
Dear colleagues!
Motiviated by a recent discussion with HS I would like to set up a simulation study to evaluate power properties of different approaches to investigate dose-proportionality. To mimic the real world situation I would like to start a little survey and discussion regarding dose selection for these kind of studies.
I would be happy to get your points of view regarding the following questions:
best regards
martin
Motiviated by a recent discussion with HS I would like to set up a simulation study to evaluate power properties of different approaches to investigate dose-proportionality. To mimic the real world situation I would like to start a little survey and discussion regarding dose selection for these kind of studies.
I would be happy to get your points of view regarding the following questions:
- how many doses are usually used in these kind of studies?
- how doses are selected? I encountered that doses are often doubled in these kind of studies (eg. 0.5 mg, 1 mg, 2 mg, 4 mg).
best regards
martin
Complete thread:
- dose selection to investigate dose-proportionalitymartin 2009-12-23 10:12
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Dose-proportionality Helmut 2009-12-23 16:16
- Dose-proportionality martin 2009-12-29 22:47
- Dose-proportionality Helmut 2009-12-23 16:16
Ing. Helmut Schütz