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RegisterMemantine? [PK / PD]
posted by Helmut 
– Vienna, Austria, 2012-08-01 17:09 (4725 d 13:06 ago) – Posting: # 9016
Views: 9,576
Dear Chiku!
Not sure what you mean there. Memantine is BCS I (see also FDA’s guidance) with a long half life, but tmax (as expected) occurs early. We found the following (in hours):
❝ There are no of BCS class I drugs having long Tmax such as mematanine.
Not sure what you mean there. Memantine is BCS I (see also FDA’s guidance) with a long half life, but tmax (as expected) occurs early. We found the following (in hours):
tmax (median, quartiles) t½ (xharm, ±SD)
2×5 mg tablets (n=12): 4.0 (4.0, 6.0) 49.7 ( 8.8)
10 mg tablets (n=36) : 5.0 (4.0, 6.0) 53.0 (10.6)
10 mg tablets (n=36) : 5.5 (4.0, 8.0) 54.4 (11.3)
10 mg Akatinol (n=36): 5.0 (4.0, 6.0) 54.9 (12.9)—
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Helmut Schütz
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Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Factors Affecting Tmax jag009 2012-05-03 23:00
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Factors Affecting Tmax luvblooms 2012-05-04 06:04
- Factors Affecting Tmax Chiku 2012-08-01 14:29
- Factors Affecting Tmax Chiku 2012-08-01 14:26
- Memantine?Helmut 2012-08-01 15:09
- Memantine? Chiku 2012-08-02 07:50
- Memantine! Helmut 2012-08-02 19:57
- Memantine! Chiku 2012-08-03 13:06
- Memantine! Helmut 2012-08-02 19:57
- Memantine? Chiku 2012-08-02 07:50
- Memantine?Helmut 2012-08-01 15:09
- Factors Affecting Tmax luvblooms 2012-05-04 06:04
Ing. Helmut Schütz