Bioequivalence and Bioavailability Forum • AntiemeticDrug selection for BE study of Carbidopa, Levodopa and Entacapone

AntiemeticDrug selection for BE study of Carbidopa, Levodopa and Entacapone [PK / PD]

posted by anky1212 – India, 2016-12-27 16:43 (3114 d 21:23 ago) – Posting: # 16886
Views: 5,976

❝ I can see two options:

if you are sure that healthy volunteers are ethically acceptable you could randomize more people to cover possible dropouts due to vomiting
❝
to utilize patients

Thanks for reply.

We are planning to enroll healthy human volunteer. My only concern is to use appropriate antiemetic drug which was used previously in trial/ BE study of LCE.

Please suggest appropriately.

Thanks

Complete thread:

AntiemeticDrug selection for BE study of Carbidopa, Levodopa and Entacapone anky1212 2016-12-27 14:50
- AntiemeticDrug selection for BE study of Carbidopa, Levodopa and Entacapone BE-proff 2016-12-27 15:08
  - AntiemeticDrug selection for BE study of Carbidopa, Levodopa and Entacaponeanky1212 2016-12-27 15:43
    - Antiemetic Drugs can change PK profiles mittyri 2016-12-27 17:15
      - Antiemetic Drugs can change PK profiles anky1212 2016-12-27 18:02
        
        Antiemetic Drugs can change PK profiles mittyri 2016-12-27 19:33
- AntiemeticDrug selection for BE study of Carbidopa, Levodopa and Entacapone luvblooms 2016-12-28 08:05