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RegisterQuantification of S-amlodipine [PK / PD]
Dear,
Amlodipine is a racemic mixture of [-]S and [+]R-enantiomeric forms, with the S-amlodipine, also known as Levamlodipine, having analgesic activity.
Considering the main objective in bioanalysis will be development an achiral method, simple, sensitive, rapid and reliable mass spectrometry for the quantification of S-amlodipine in human plasma. I ask you,...can I use Amlodipine (racemic) instead of S-amlodipine (enantiomeric form) as analitical standard?
Note: The volunteers just will administrate Levamlodipine.
Amlodipine is a racemic mixture of [-]S and [+]R-enantiomeric forms, with the S-amlodipine, also known as Levamlodipine, having analgesic activity.
Considering the main objective in bioanalysis will be development an achiral method, simple, sensitive, rapid and reliable mass spectrometry for the quantification of S-amlodipine in human plasma. I ask you,...can I use Amlodipine (racemic) instead of S-amlodipine (enantiomeric form) as analitical standard?
Note: The volunteers just will administrate Levamlodipine.
Complete thread:
- Linear Pharmacokinetics of Levamlodipine Mauricio Sampaio 2015-10-07 00:24
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Linear Pharmacokinetics of Levamlodipine Mauricio Sampaio 2016-06-03 22:33
- Quantification of S-amlodipineMauricio Sampaio 2016-06-06 16:19
- Quantification of S-amlodipine Helmut 2016-06-06 20:23
- Quantification of S-amlodipine nobody 2016-06-07 08:29
- Quantification of S-amlodipine Mauricio Sampaio 2016-06-07 18:35
- Quantification of S-amlodipine Helmut 2016-06-08 01:32
- Quantification of S-amlodipine Mauricio Sampaio 2016-06-09 21:48
- Quantification of S-amlodipine Helmut 2016-06-08 01:32
- Quantification of S-amlodipine Mauricio Sampaio 2016-06-07 18:35
- Quantification of S-amlodipine nobody 2016-06-07 08:29
- Quantification of S-amlodipine Helmut 2016-06-06 20:23
- Quantification of S-amlodipineMauricio Sampaio 2016-06-06 16:19
- Linear Pharmacokinetics of Levamlodipine martin 2016-06-09 15:22
- Linear Pharmacokinetics of Levamlodipine Mauricio Sampaio 2016-06-09 22:03
- Linear Pharmacokinetics of Levamlodipine martin 2016-06-12 21:48
- Linear Pharmacokinetics of Levamlodipine Mauricio Sampaio 2016-06-09 22:03
- Linear Pharmacokinetics of Levamlodipine Mauricio Sampaio 2016-06-03 22:33
Ing. Helmut Schütz