Bioequivalence and Bioavailability Forum • solve for k01?

solve for k01? [PK / PD]

posted by Helmut – Vienna, Austria, 2013-07-17 18:08 (4375 d 20:13 ago) – Posting: # 10999
Views: 22,685

Hi John,

❝ Could someone solve the k01 term from the 1 compartment w lag time model?

❝

❝ C(t) = DK₀₁/V(K₀₁-K₁₀) * (e^{(-K₁₀*(t-t_lag))} - e^{(-k₀₁*(t-t_lag))})

I was missing some () in your formula… What do you mean by ‘solve’? Can you elaborate?

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz

[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

1 compartment model with lag time jag009 2013-07-17 15:58
- solve for k01?Helmut 2013-07-17 16:08
  - solve for k01? jag009 2013-07-17 16:19
    - solve for k01? ElMaestro 2013-07-17 17:09
    - no closed form Helmut 2013-07-17 23:01
- 1 compartment model with lag time yjlee168 2013-07-17 20:57
- Package-free solution ElMaestro 2013-07-17 21:53
  - Package-free solution yjlee168 2013-07-17 22:11
    - Package-free solution ElMaestro 2013-07-17 22:27
      - Package-free solution yjlee168 2013-07-17 22:42
  - Package-free solution ElMaestro 2013-07-17 23:21
    - A new R-King was born d_labes 2013-07-18 08:45
      - Brent ElMaestro 2013-07-18 09:07
      - A new R-King was born yjlee168 2013-07-18 10:21
        
        OT: TTT in bear Helmut 2013-07-18 20:28
        
        OT: TTT in bear yjlee168 2013-07-18 22:17
        
        OT: TTT subtleties d_labes 2013-07-19 09:47
        
        OT: TTT subtleties yjlee168 2013-07-20 19:44
        
        OT: beyond TTT? Helmut 2013-07-21 00:08
        
        OT: beyond TTT? yjlee168 2013-07-22 13:45
        
        OT: keep TTT! Helmut 2013-07-22 14:21
        
        OT: keep TTT! yjlee168 2013-07-22 23:42
        
        OT: EOD (here) Helmut 2013-07-23 01:06
    - Package-free solution yjlee168 2013-07-18 10:27
      - Thank you guys! jag009 2013-07-18 16:37
        
        Thank you guys! ElMaestro 2013-07-18 18:57
        
        Thank you guys! jag009 2013-07-19 20:40

Admin contact
23,428 posts in 4,929 threads, 1,683 registered users;
36 visitors (0 registered, 36 guests [including 12 identified bots]).
Forum time: 14:21 CEST (Europe/Vienna)

To know that we know what we know,
and to know that we do not know what we do not know,
that is true knowledge. Nicolaus Copernicus

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC

Ing. Helmut Schütz