Bioequivalence and Bioavailability Forum

package PK [🇷 for BE/BA]

posted by d_labes  – Berlin, Germany, 2010-04-20 16:35 (5894 d 08:11 ago) – Posting: # 5174
Views: 10,068

Dear Helmut,

❝ Estimation for a complete data design

❝

❝ [code]                  AUC     AUMC

❝ observed     69.47000 156.1381

❝ interpolated       NA       NA

❝ infinity     74.80844 198.2036

How did you do that .
If I run your code I always get only an error:
> auc(conc,time,design='complete')
Error in quantile.default(stat, alpha/2, method = 5) :
  missing values and NaN's not allowed if 'na.rm' is FALSE

Used by me:
PK Version 1.2-1
R 2.10.0

If I specify a method in the auc() call I get
> auc(conc, time, group=NULL, design='complete',method="t")
Estimation for a complete data design

             Estimate SE 95% t-CI
AUC to tlast    69.47 NA  (NA;NA)

Complete thread:

• Trapezoidal rule - Hmisc d_labes 2010-04-19 13:41 
  • Trapezoidal rule - PK Helmut 2010-04-20 12:53
    • package PKd_labes 2010-04-20 14:35
      • package PK Jack 2010-04-20 15:21
      • Syntax... Helmut 2010-04-20 15:31
      • package PK Jack 2010-04-23 17:00
        • package PK d_labes 2010-04-26 08:04