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Register90% CIs for BE? [🇷 for BE/BA]
Dear Yung-jin,
it really sounds interesting if FDA will be using Pharsight's software.
Did I really write interesting?? I of course meant horrible!
Remember the type III discussion? There is not agreement about them among statisticians but since FDA published source scripts based on SAS (which uses type III SS by default) they have somehow become a de facto standard.
I could easily imagine a similar phenomenon will reveal itself with Pharsight's software. PK analyses in the world's companies then will be a struggle to reproduce the output of WinNonlin etc rather than a scientific exercise that strives to do it properly.
EM.
it really sounds interesting if FDA will be using Pharsight's software.
Did I really write interesting?? I of course meant horrible!
Remember the type III discussion? There is not agreement about them among statisticians but since FDA published source scripts based on SAS (which uses type III SS by default) they have somehow become a de facto standard.
I could easily imagine a similar phenomenon will reveal itself with Pharsight's software. PK analyses in the world's companies then will be a struggle to reproduce the output of WinNonlin etc rather than a scientific exercise that strives to do it properly.
EM.
Complete thread:
- 90% CIs for BE? yjlee168 2008-11-17 08:52
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- 90% CIs for BE? ElMaestro 2008-11-17 09:46
- 90% CIs for BE? d_labes 2008-11-17 13:07
- There can be only one! Helmut 2008-11-17 17:12
- 90% CIs for BE? Helmut 2008-11-17 13:30
- 90% CIs for BE? ElMaestro 2008-11-17 13:51
- 90% CIs for BE? d_labes 2008-11-17 13:56
- 90% CIs for BE? yjlee168 2008-11-17 18:10
- 90% CIs for BE? Helmut 2008-11-17 18:14
- 90% CIs for BE? yjlee168 2008-11-17 18:26
- 90% CIs for BE?ElMaestro 2008-11-17 19:49
- 90% CIs for BE? yjlee168 2008-11-17 18:26
- 90% CIs for BE? Helmut 2008-11-17 18:14
- 90% CIs for BE? ElMaestro 2008-11-17 13:51
Ing. Helmut Schütz