Bioequivalence and Bioavailability Forum

S×F variance: Followup [General Statistics]

posted by jag009 – NJ, 2015-01-08 23:42 (3836 d 19:13 ago) – Posting: # 14263
Views: 42,777

Hi Angus,

Finally had some time to do this quickly. I apologize as I made a typo in my SAS code for the 95% UCB computation. My results are similar to yours

Par dfd    Var(σ2)        Cinv

W_T   69  0.116539674     89.39120787

W_R   71  0.199313551     91.67023918

W_I   67  0.165897781     49.16227018

So, the only differences between our results are with W_T. My dfd is 69 while yours is 67, and the slight difference in Var(σ2). If you count the number of subjects who has both T1 & T2 data, there are 69. I think the number of subjects used in the computation for test is the culprit (in Phoenix). For R, there are 71 subjects who completed both R1 and R2.

For me, σ²_D = 0.0079711687

Using the above,

Hσ²_D = ΣEQ + (ΣU)^1/2 = 0.073582621

I haven't done this exercise in Phoenix though so I don't know how it didn't end up with n=69 for Test at your end.

Thanks
John

Complete thread:

S×F variance Helmut 2014-12-23 15:32
- S×F variance AngusMcLean 2014-12-23 16:32
  - S×F variance Helmut 2014-12-23 17:17
    - S×F variance AngusMcLean 2014-12-28 23:12
- S×F variance AngusMcLean 2014-12-23 20:56
- S×F variance jag009 2014-12-23 23:07
  - S×F variance AngusMcLean 2014-12-24 01:39
    - S×F variance jag009 2014-12-24 16:21
      - S×F variance AngusMcLean 2014-12-24 17:50
  - S×F variance AngusMcLean 2015-01-06 17:30
    - S×F variance: Followupjag009 2015-01-08 22:42
      - S×F variance: Followup AngusMcLean 2015-01-09 01:44
        
        S×F variance: Followup jag009 2015-01-12 16:53
        
        S×F variance: Followup AngusMcLean 2015-01-12 20:56
        
        S×F variance: 3rd opinion Helmut 2015-01-13 01:25
        
        S×F variance: 3rd opinion AngusMcLean 2015-01-13 20:13
        S×F variance: 3rd opinion AngusMcLean 2015-01-14 21:29
        
        S×F variance: 3rd opinion jag009 2015-01-14 23:00
        
        α vs. 1–α Helmut 2015-01-15 00:54
        
        α vs. 1–α jag009 2015-01-15 22:38
        
        α vs. 1–α Helmut 2015-01-16 00:13
        
        α vs. 1–α jag009 2015-01-19 20:09
        
        α vs. 1–α jag009 2015-01-19 16:02
        
        S×F variance: 3rd opinion AngusMcLean 2015-01-29 23:38
        
        S×F variance: Followup AngusMcLean 2015-01-30 23:24
        
        S×F variance: Followup jag009 2015-02-02 16:31
        
        S×F variance: Followup AngusMcLean 2015-02-02 17:22
        
        S×F variance: Followup jag009 2015-02-05 18:14
        
        S×F variance: Followup AngusMcLean 2015-02-06 01:39
        
        S×F variance: Followup jag009 2015-02-06 17:13
        
        S×F variance: Followup AngusMcLean 2015-02-06 19:36
        
        S×F variance: Followup jag009 2015-02-17 22:49
        
        S×F variance: Followup AngusMcLean 2015-02-19 23:25
        
        S×F variance: Followup jag009 2015-02-21 21:08
        
        S×F variance: Followup AngusMcLean 2015-02-22 17:25
        
        S×F variance: Followup jag009 2015-02-23 16:58
- S×F variance AngusMcLean 2015-01-06 18:48
  - S×F variance jag009 2015-01-07 21:28
    - S×F variance Helmut 2015-01-08 16:10
      - S×F variance: Typo. jag009 2015-01-08 17:32
        
        S×F variance AngusMcLean 2015-01-08 18:51
        
        S×F variance jag009 2015-01-08 20:02
        
        S×F variance AngusMcLean 2015-01-08 20:27
        
        S×F variance jag009 2015-01-08 20:33

S×F vari­­ance: Followup [General Sta­tis­tics]

Complete thread:

S×F variance: Followup [General Statistics]