Bioequivalence and Bioavailability Forum

Hi Ravindra,

I was taking primarily about the matrix. In this case serum is one step further away from the site of action.
Imagine you consume garlic. Either you could measure alliin or allicin in plasma or allyl methyl sulfide in exhaled air. What would you do?

❝ IN my terms if you prove both passes your product is really bio equivalent.

By (IMHO, erroneously) assuming that total iron is representative of the small amount of absorbed iron on top of the large endogenous pool…

❝ also it is important to note that ICPMS is not the appropriate method.

Why not?