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RegisterECG during the Moxifloxacin study [Study Performance]
Dear mittyri
I would like to point out that follow-up controls of ECG are at the responsibility of the principal investigator and (s)he must decide what needs to be done i.e. how many ECG need to be recorded. Delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsades de pointes. These episodes may lead to palpitations, fainting, and sudden death due to ventricular fibrillation. Therefore, IMHO ECG must be monitored before and after drug administration. Following a 400 mg oral dose peak concentrations of 3.1 mg/l are reached within 0.5 - 4 h post administration. At least this period of time needs to be monitored.
I hope this helps.
Kind regards
Dr_Dan
I would like to point out that follow-up controls of ECG are at the responsibility of the principal investigator and (s)he must decide what needs to be done i.e. how many ECG need to be recorded. Delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsades de pointes. These episodes may lead to palpitations, fainting, and sudden death due to ventricular fibrillation. Therefore, IMHO ECG must be monitored before and after drug administration. Following a 400 mg oral dose peak concentrations of 3.1 mg/l are reached within 0.5 - 4 h post administration. At least this period of time needs to be monitored.
I hope this helps.
Kind regards
Dr_Dan
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Kind regards and have a nice day
Dr_Dan
Kind regards and have a nice day
Dr_Dan
Complete thread:
- ECG during the Moxifloxacin study mittyri 2014-07-22 21:00
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- ECG during the Moxifloxacin study Samaya B 2014-07-23 09:00
- ECG during the Moxifloxacin studyDr_Dan 2014-07-23 12:02
Ing. Helmut Schütz