Bioequivalence and Bioavailability Forum

Sample size calculation using Marzo and Balant method [Power / Sample Size]

posted by kumarnaidu – Mumbai, India, 2013-01-31 08:48 (4537 d 15:23 ago) – Posting: # 9933
Views: 13,909
(edited on 2013-01-31 10:19)

Hello everyone
In the below given article (in red) there is a statement for sample size calculation "Sample size was calculated using the formula developed by Marzo and Balant, using Cmax CVs of 38% for TDF and of 24% for 3TC, according to literature". Can anybody please tell me what is Marzo and Balant method for sample size calculation .

Single-Dose Bioequivalence of a New Fixed-Dose Combination Tablet Containing Tenofovir Disoproxil Fumarate and Lamivudine
Feleder Ethel C, Yerino Gustavo A, Halabe Emilia K, Carla Serebrinsky, Soledad Gonzalez and Zini Elvira

Thanks in advance......

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Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]
Edit: See doi:10.4172/jbb.1000093. [Helmut]

Complete thread:

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      • Quality vs. Clinical ElMaestro 2012-11-20 09:04
  • Sample size? Helmut 2012-11-20 20:10
    • Sample size? The Outlaw Torn 2012-11-21 07:52
    • Sample size? The Outlaw Torn 2012-11-22 10:55
      • Sample size, ratio, CV ↔ power Helmut 2012-11-22 13:35
        • Sample size, ratio, CV ↔ power The Outlaw Torn 2012-11-23 14:47
        • Sample size, ratio, CV ↔ power BEQool 2025-01-31 13:12
          • TOST != treatment effect mittyri 2025-02-20 13:13
          • Sample size, ratio, CV ↔ power zizou 2025-02-21 13:40
            • Not vice versa mittyri 2025-02-22 21:08
              • Not vice versa? zizou 2025-02-24 11:02
                • Not vice versa? mittyri 2025-02-25 06:12
  • Sample size calculation using Marzo and Balant methodkumarnaidu 2013-01-31 07:48
    • Marzo / Balant formula d_labes 2013-01-31 10:05
      • Marzo / Balant formula kumarnaidu 2013-01-31 10:54
        • Marzo / Balant formula kumarnaidu 2013-02-04 05:48
          • Marzo / Balant formula for parallel groups d_labes 2013-02-04 08:44