Bioequivalence and Bioavailability Forum

The grandiose shocker of 2020 ElMaestro 2020-07-22 13:17
- The most obscure post ever Helmut 2020-07-22 13:51
  - Here goes ElMaestro 2020-07-22 14:34
    - Yeah but, no but, yeah but… Helmut 2020-07-22 15:37
      - Yeah but, no but, yeah but… ElMaestro 2020-07-22 17:53
    - Here goes PharmCat 2020-07-29 21:11
- The grandiose shocker of 2020 jag009 2020-07-24 18:52
  - The grandiose shocker of 2020 ElMaestro 2020-07-24 19:01

BA drift Helmut 2020-07-21 15:10

Concentration Statistics - BQL substitution SaraCHenriques 2020-07-01 14:37
- Concentration Statistics - BQL substitution Helmut 2020-07-01 15:27
  - Concentration Statistics - BQL substitution martin 2020-07-02 09:37
    - Data imputation Helmut 2020-07-02 11:15
    - Concentration Statistics - BQL substitution ElMaestro 2020-07-02 13:48
      - Concentration Statistics - BQL substitution martin 2020-07-02 14:52
    - Concentration Statistics - BQL substitution Ben 2020-07-07 16:37
      - BQL in BE and PK modeling Helmut 2020-07-08 10:23
      - Concentration Statistics - BQL substitution ElMaestro 2020-07-08 11:35
      - Roger again mittyri 2020-07-08 12:03

higher order crossover methodology sweiner 2020-06-30 01:07
- All dosed subjects have to be analyzed Helmut 2020-06-30 12:19
  - All dosed subjects have to be analyzed sweiner 2020-06-30 17:08
- higher order crossover methodology Relaxation 2020-06-30 14:10
  - higher order crossover methodology sweiner 2020-06-30 17:10
    - higher order crossover methodology ElMaestro 2020-06-30 18:17
      - Fed (IBD) → fasting Helmut 2020-07-01 11:14
        
        Fed (IBD) → fasting sweiner 2020-07-07 03:00

Statistical independence, what is it? I mean really, what is it?? ElMaestro 2020-06-27 21:35
- Die don’t remember the last roll. Really. Helmut 2020-06-28 13:35
  - Die don’t remember the last roll. Really. ElMaestro 2020-06-28 14:45
    - Die don’t remember the last roll. Really. Helmut 2020-06-28 15:36
      - Still none the wiser ElMaestro 2020-06-28 18:20
        
        You’ve lost me now. Helmut 2020-06-28 21:55
        
        Worded differently ElMaestro 2020-06-29 08:30
        
        Still not sure what you are aiming at… Helmut 2020-06-29 16:46
        
        Still not sure what you are aiming at… ElMaestro 2020-06-30 00:55
        
        Confuse-a-Cat Helmut 2020-06-30 11:33
        
        Confuse-a-Cat ElMaestro 2020-06-30 13:07
        
        Confuse-a-Cat Helmut 2020-06-30 14:27
        pseudorandom and linear independence mittyri 2020-07-01 00:04
- Statistical independence, what is it? I mean really, what is it?? martin 2020-07-01 08:40
  - Statistical independence, what is it? I mean really, what is it?? ElMaestro 2020-07-01 09:42
    - Statistical independence, what is it? I mean really, what is it?? martin 2020-07-01 10:07

truncation issues Loky do 2020-06-24 03:23
- EMA: AUC72 for all IR products Helmut 2020-06-24 10:47
  - EMA: AUC72 for all IR products pmohite 2020-06-24 12:08

protocol amendment that may trigger Group effect test Silke 2020-03-24 08:52
- protocol amendment that may trigger Group effect test ElMaestro 2020-03-24 09:07

ANOVA MODEL abhimanyu 2020-02-04 05:31
- No random effects in ANOVA Helmut 2020-02-04 11:33
  - No random effects in ANOVA abhimanyu 2020-02-05 12:47

On CI calculation, untransformed metrics ElMaestro 2019-11-29 03:40
- Fieller’s (‘fiducial’) confidence interval Helmut 2019-11-29 10:03
  - Fieller’s (‘fiducial’) confidence interval ElMaestro 2019-11-29 15:53
    - Fieller’s (‘fiducial’) confidence interval d_labes 2019-11-29 17:20
      - Fieller’s (‘fiducial’) confidence interval ElMaestro 2019-11-30 05:11
        
        power.TOST with logscale=FALSE d_labes 2019-11-30 14:01
- On CI calculation, untransformed metrics PharmCat 2019-11-29 12:05

Power Model Vivek Chaudhari 2019-11-27 07:12
- Power Model Helmut 2019-11-27 14:35

What is the largest α (Alpha) & β (Beta) allowed by FDA? victor 2019-11-16 21:57
- What do you want to achieve? Helmut 2019-11-17 01:26
  - I'm seeking to understand the math behind our current regulation victor 2019-11-17 10:53
    - Some answers Helmut 2019-11-17 14:35
      - Wow! Amazing answers! victor 2019-11-18 08:26
        
        More answers Helmut 2019-11-18 15:09
        
        Wow! More amazing answers! victor 2019-11-18 20:16
        
        Books & intersection-union Helmut 2019-11-19 12:01
        
        My progress on IUT so far victor 2019-11-22 01:28
        
        Update: Counterexamples victor 2019-11-23 09:05

Least square mean calculation for the fully replicate design Jaimik Patel 2019-10-31 11:19
- Very, very strange! Helmut 2019-10-31 14:36
  - Very, very strange! Shuanghe 2019-10-31 19:43
    - Very, very strange! Helmut 2019-10-31 19:50
  - Very, very strange! Jaimik Patel 2019-11-02 12:26
    - G matrix mittyri 2019-11-03 01:38
- Inner workings of REML ElMaestro 2019-10-31 19:48
  - Even in ANOVA… Helmut 2019-10-31 19:53
    - Even in 2x2... zizou 2019-11-01 21:05
      - trying to understand emmeans mittyri 2019-11-02 02:26
- Least square mean calculation for the fully replicate design PharmCat 2019-11-03 00:46

Group by sequence interaction Mutasim 2019-08-07 13:16
- Group by sequence interaction, an urban myth? Helmut 2019-08-07 14:35
  - pristine, genuine, holy, magnificent, inexplicable beautiful variation ElMaestro 2019-08-08 10:06
    - I love your subject line! Helmut 2019-08-08 10:31
      - Group effect, did you miss it? Astea 2019-12-21 14:12
        
        Group effect, did you miss it? PharmCat 2019-12-22 01:37
        Group effect: the endless story Helmut 2019-12-22 10:30
        
        Group effect: the endless river Astea 2019-12-22 21:23
        
        Group effect: the endless river PharmCat 2019-12-22 22:52
        replicateBE solution with interactions mittyri 2019-12-23 14:30
        
        replicateBE solution with interactions Astea 2019-12-23 17:26
        
        datasets issues mittyri 2019-12-24 10:53
        datasets Helmut 2019-12-24 11:03
        
        datasets Astea 2019-12-24 19:18
        
        lmer / lme Helmut 2019-12-25 19:12
        
        What do you mean exactly? Beholder 2019-12-27 13:44
        
        What do you mean exactly? Astea 2019-12-29 21:59
        
        ANOVA acc. to GL Helmut 2019-12-30 12:32

Indirect adjusted comparisons in BE Helmut 2019-07-21 15:20
- Pragmatic assumptions mittyri 2019-07-22 01:46
- Indirect adjusted comparisons in BE Shuanghe 2019-07-22 09:53
  - Indirect adjusted comparisons in BE nobody 2019-07-22 13:32
    - Indirect adjusted comparisons in BE Shuanghe 2019-07-22 15:20
  - Indirect adjusted comparisons in BE Helmut 2019-07-22 15:45
    - Indirect adjusted comparisons in BE nobody 2019-07-22 18:38

biostatistics Aida hassan 2019-06-13 15:29

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